Zithromax: History, Effects and Adverse Effects of Azithromycin

Zithromax, also known as Azithromycin, is a widely used antibiotic that belongs to the macrolide class of antibiotics. It is used to treat a variety of bacterial infections, including respiratory infections, skin infections, and sexually transmitted infections. Zithromax is available in several different forms, including tablets, capsules, and oral suspension.

One of the key advantages of Zithromax is its broad-spectrum activity against many different types of bacteria. This makes it a popular choice for treating a wide range of infections, including those caused by atypical bacteria that may be resistant to other antibiotics.

Zithromax has its share of adverse effects. It’s not a particularly dangerous drug, but it should still be taken exactly as prescribed. If you don’t, there is a risk of encountering several uncomfortable side effects, as well as long-term negative consequences – in particular, ones related to the cardiovascular system.


Zithromax was first approved for use in the United States by the FDA in 1991 and quickly became a popular choice among healthcare providers due to its effectiveness. Azithromycin was developed by the pharmaceutical company Pfizer, whereas Zithromax is its brand name.

The discovery of Azithromycin can be traced back to the 1980s when a team of researchers at Pfizer began working on a new class of antibiotics called macrolides. These antibiotics are structurally related to erythromycin and have a similar mechanism of action but with improved pharmacokinetics.

After several years of research, Azithromycin was identified as a promising candidate and entered clinical trials in 1985. The tests ended in 1991 when FDA finally approved this antibiotic. That was fortunate, considering that Zithromax targets some conditions that other solutions are very ineffective at dealing with. This made this drug hugely popular.

Right now, Zithromax is one of the most widespread antibiotics in the world.

Understanding Azalides

Zithromax is an azalide. They are a special type of antibiotics that target a specific group of conditions more effectively. They work by interfering with the bacteria’s ability to produce proteins, which are necessary for their survival and reproduction. Essentially, they slow down the growth of bacteria, allowing the immune system to kill the rest.

What they do to the cells of these bacteria is a long story. Essentially, they interact with the ribosome, an important part of a cell tasked with creating protein for further growth and reproduction. This ultimately results in the cessation of bacterial replication and growth.

Azalides have a unique property that sets them apart from other antibiotics. They have a little nitrogen atom inside them, which enhances their activity against a broader range of bacteria. It also means greater stability and resistance to the stomach acids. It means it’s absorbed into the blood faster and is more efficient against bacteria.

Azalides are also great at improving your immune system, which creates a double-pronged punch of sorts against various conditions. Thus, the azalides are more powerful against inflammatory diseases, including cystic fibrosis, chronic obstructive pulmonary disease, and others.


Zithromax is one of the foremost azalides on the market, making it a good choice against a wide variety of bacterial infections. As mentioned, it works by decreasing the ability of foreign bacteria to reproduce and grow. Moreover, it boosts the immune system, making it easier for the body to expel the already existing invaders.

It makes it a relatively fast-acting solution, capable of eliminating the infection within 3-10 days. Of course, it depends on the type and intensity of the condition, but it doesn’t usually take more than that. You should take the exact dose prescribed by the doctor every day at the same time.

The dose is usually 500-1000mg, regardless of food intake. If the condition is particularly nasty, the dose can be increased to even 2000mg. The higher doses, however, become increasingly unsafe. Zithromax can have very uncomfortable side effects, although it is overall a safe enough drug.

Adverse Effects of Zithromax

Some frequent side effects of Zithromax include stomachache, diarrhea, and nausea. You’ll likely encounter these if you ever take large doses of Zithromax, but they generally go away relatively fast. Liver problems and arrhythmia are some of the less frequent, but more serious problems.

These rarely occur on their own, but if you take too much of this drug, it’s bound to happen. A Zithromax overdose can be fatal if taken in very excessive amounts, but more often than not you’ll experience the same liver problems and arrhythmia as mentioned above. In this case, you should absolutely seek medical help.


This is an overview and does NOT contain every possible detail about this product. This data does not guarantee that this product is secure, efficient, or suitable for your needs. This information is not personalized medical guidance and does not replace the counsel of your healthcare specialist. Always consult your healthcare professional for comprehensive information about this product and your unique health requirements.